R J Hajjar Selected Research

Sarcoplasmic Reticulum Calcium-Transporting ATPases

12/2020	Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL.
3/2016	Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure.
9/2001	Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure.
1/2000	Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

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R J Hajjar Research Topics

Disease

12	Heart Failure 12/2020 - 01/2000
4	Myocardial Infarction 01/2019 - 01/2009
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2016 - 11/2001
3	Infections 04/2013 - 02/2000
2	Cardiomyopathies (Cardiomyopathy) 01/2017 - 01/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2016 - 06/2012
2	Infarction (Infarctions) 01/2009 - 09/2006
2	Hypertrophy 03/2001 - 01/2000
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2016
1	Thrombosis (Thrombus) 09/2013
1	Hyperplasia 09/2013
1	Hypertension (High Blood Pressure) 06/2012
1	Inflammation (Inflammations) 06/2012
1	Pericardial Effusion 10/2011
1	Type 2 Diabetes Mellitus (MODY) 07/2009
1	Insulin Resistance 07/2009
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2007
1	Fibrosis (Cirrhosis) 10/2004
1	Hypoxia (Hypoxemia) 07/2001
1	Heart Diseases (Heart Disease) 07/2001
1	Contracture 05/2001
1	Cardiomegaly (Heart Hypertrophy) 03/2001

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2000
8	CalciumIBA 06/2012 - 01/2000
4	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 12/2020 - 01/2000
3	Adenosine Triphosphatases (ATPase)IBA 12/2008 - 02/2000
2	Protein Isoforms (Isoforms)IBA 12/2020 - 10/2004
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 02/2012
1	Saline SolutionIBA 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	Neutralizing AntibodiesIBA 03/2016
1	Clopidogrel (Plavix)FDA Link 01/2016
1	CationsIBA 01/2016
1	DystrophinIBA 01/2016
1	Cytochrome P-450 CYP2C19IBA 01/2016
1	GalactosidasesIBA 04/2013
1	3-methyladenineIBA 02/2012
1	enhanced green fluorescent proteinIBA 10/2011
1	LipidsIBA 07/2009
1	Lipoproteins (Lipoprotein)IBA 07/2009
1	Blood Glucose (Blood Sugar)IBA 07/2009
1	Apolipoproteins E (ApoE)IBA 07/2009
1	ApolipoproteinsIBA 07/2009
1	Glucose (Dextrose)FDA LinkGeneric 07/2009
1	Insulin (Novolin)FDA Link 07/2009
1	Erythropoietin FDA Link 01/2009
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2007
1	SilverIBA 07/2006
1	Adrenergic Agents (Adrenergic Drugs)IBA 04/2005
1	Cytoskeletal ProteinsIBA 10/2004
1	ConnectinIBA 10/2004
1	Carteolol (Carteolol Hydrochloride)FDA LinkGeneric 11/2001
1	beta Adrenergic ReceptorsIBA 11/2001
1	CatecholaminesIBA 03/2001
1	CalcineurinIBA 03/2001
1	Tacrolimus (Prograf)FDA LinkGeneric 03/2001
1	Phosphotransferases (Kinase)IBA 03/2001
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 03/2001
1	beta-Galactosidase (Lactaid)IBA 01/2000

Therapy/Procedure

4	Therapeutics 01/2017 - 07/2001
2	Catheters 09/2001 - 01/2000
1	Heart-Assist Devices 12/2020
1	Ligation 01/2019
1	Stents 09/2013
1	Percutaneous Coronary Intervention 09/2013
1	Punctures 10/2011
1	Absorbable Gelatin Sponge 10/2011
1	Drug Therapy (Chemotherapy) 01/2006